The Ene Lab is part of the Mycology Department at the Pasteur Institute (Paris, France).
Our work is focused on understanding how fungal cells respond and adapt to drugs. In particular, we study how individual differences between cells can allow Candida populations to escape antifungal inhibition. Antifungal tolerance and heteroresistance have been recently described in fungi and we seek to understand the mechanisms enabling these phenomena. To address these questions, we combine tools in molecular biology, genomics, transcriptomics, and animal models of infections.
Interested in working with us?
We are looking for motivated students and postdocs to join our team. To apply, please email Jules
.
We currently have a postdoc position on an ANR funded project. Read more about it here.
Iuliana (Jules) Ene
I am currently a CIFAR Global Scholar in the Fungal Kingdom: Threats & Opportunities Program. Previously, I was a Research Assistant Professor of Molecular Microbiology and Immunology at Brown University. Prior to starting my group at Brown, I did a postdoc with Prof Richard Bennett in the same department. I received my PhD from the University of Aberdeen in 2012, where I worked with Prof Al Brown as part of the Aberdeen Fungal Group (now the MRC Center for Medical Mycology).Publications
McDonough L, Mishra AA, Tosini N, Kakade P, Penumutchu S, Liang SH, Maufrais C, Zhai B, Taur Y, Belenky P, Bennett RJ*, Hohl TM*, Koh AY*, Ene IV*
mBio 2021
Ene IV, Hickman MA, Gerstein AC
Current Clinical Microbiology Reports 2021
Thomson GJ, Kakade P, Hirakawa MP, Ene IV*, Bennett RJ*
G3 Genes| Genomes| Genetics 2021
Beekman CN, Cuomo CA, Bennett RJ, Ene IV
G3 Genes| Genomes| Genetics 2021
Beekman CN, Ene IV
PLoS Pathogens 2020
Ene IV, Bennett RJ, Anderson MZ
Current Opinion in Microbiology 2019
Liang SH, Anderson MZ, Hirakawa MP, Wang JM, Frazer C, Alaalm LM, Thomson GJ, Ene IV, Bennett RJ
Cell Host and Microbe 2019
Ene IV, Farrer RA, Hirakawa MP, Agwamba K, Cuomo CA, Bennett RJ
PNAS 2018
Rosenberg A*, Ene IV*, Bibi M, Zakin S, Segal ES, Ziv N, Dahan AM, Colombo AL, Bennett RJ, Berman J
Nature Communications 2018
*indicates equal contributions
associated article on the Nature Microbiology Community blog
Ene IV, Lohse MB, Vladu AV, Morschhäuser J, Johnson AD, Bennett RJ
mBio 2016
Lohse MB, Ene IV, Craik VB, Hernday AD, Mancera E, Morschhäuser J, Bennett RJ, Johnson AD
Genetics 2016
Ene IV, Walker LA, Schiavone M, Lee KK, Martin-Yken H, Dague E, Gow NA, Munro CA, Brown AJ
mBio 2015
Ene IV, Brunke S, Brown AJ, Hube B
Cold Spring Harbor Perspectives in Medicine 2014
Ene IV, Bennett RJ
Nature Reviews Microbiology 2014
Ene IV, Brown AJ
Fungal Genomics, The Mycota XIII 2014 (book chapter)
Brown AJ, Budge S, Kaloriti D, Tillmann A, Jacobsen MD, Yin Z, Ene IV, Bohovych I, Sandai D, Kastora S, Potrykus J, Ballou ER, Childers DS, Shahana S, Leach MD
Journal of Experimental Biology 2014
Ene IV, Cheng SC, Netea MG, Brown AJ
Infection and Immunity 2013 (journal cover)
Sandai D, Yin Z, Selway L, Stead D, Walker J, Leach MD, Bohovych I, Ene IV, Kastora S, Budge S, Munro CA, Odds FC, Gow NA, Brown AJ
mBio 2012
Ene IV, Heilmann CJ, Sorgo AG, Walker LA, de Koster CG, Munro CA, Klis FM, Brown AJ
Proteomics 2012 (journal cover)
Ene IV, Adya AK, Wehmeier S, Brand AC, MacCallum DM, Gow NA, Brown AJ
Cellular Microbiology 2012 (editor's choice)
Ene IV, Bennett RJ
Eukaryotic Cell 2009